Blar i forfatter "Jørgensen, Jorunn"

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    • Detection of specific Atlantic salmon antibodies against salmonid alphavirus using a bead-based immunoassay 

      Teige, Lena Hammerlund; Aksnes, Ida; Røsæg, Magnus Vikan; Jensen, Ingvill; Jørgensen, Jorunn; Sindre, Hilde; Collins, Catherine; Collet, Bertrand; Rimstad, Espen; Dahle, Maria; Boysen, Preben (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-30)
      Salmonid alphavirus (SAV) is the etiological cause of pancreas disease (PD) in Atlantic salmon (<i>Salmo salar</i>). Several vaccines against SAV are in use, but PD still cause significant mortality and concern in European aquaculture, raising the need for optimal tools to monitor SAV immunity. To monitor and control the distribution of PD in Norway, all salmonid farms are regularly screened for SAV ...

    • The importance of the Atlantic salmon peritoneal cavity B cell response: Local IgM secreting cells are predominant upon Piscirickettsia salmonis infection 

      van der Wal, Yorick Andreas; Jenberie, Shiferaw; Nordli, Henriette; Greiner-Tollersrud, Linn; Kool, Jaap; Jensen, Ingvill; Jørgensen, Jorunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-01)
      The intraperitoneal route is favored for administration of inactivated and attenuated vaccines in Atlantic salmon. Nevertheless, the immune responses in the teleost peritoneal cavity (PerC) are still incompletely defined. In this study, we investigated the B cell responses after intraperitoneal Piscirickettsia salmonis (P. salmonis) challenge of Atlantic salmon, focusing on the local PerC response ...

    • Infection and microbial molecular motifs modulate transcription of the interferon-inducible gene ifit5 in a teleost fish 

      Bela-Ong, Dennis; Greiner-Tollersrud, Linn; van der Wal, Yorick Andreas; Jensen, Ingvill; Seternes, Ole Morten; Jørgensen, Jorunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-21)
      Interferon-induced proteins with tetratricopeptide repeats (IFITs) are involved in antiviral defense. Members of this protein family contain distinctive multiple structural motifs comprising tetratricopeptides that are tandemly arrayed or dispersed along the polypeptide. IFIT-encoding genes are upregulated by type I interferons (IFNs) and other stimuli. IFIT proteins inhibit virus replication by ...

    • Piscine Orthoreovirus (PRV)-3, but Not PRV-2, Cross-Protects against PRV-1 and Heart and Skeletal Muscle Inflammation in Atlantic Salmon 

      Malik, Muhammad Salman; Teige, Lena Hammerlund; Braaen, Stine; Olsen, Anne Berit; Nordberg, Monica; Amundsen, Marit; Kannimuthu, Dhamotharan; Svenning, Steingrim; Edholm, Eva-Stina Isabella; Takano, Tomokazu; Jørgensen, Jorunn; Wessel, Øystein; Rimstad, Espen; Dahle, Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-06)
      Heart and skeletal muscle inflammation (HSMI), caused by infection with Piscine orthoreovirus-1 (PRV-1), is a common disease in farmed Atlantic salmon (Salmo salar). Both an inactivated whole virus vaccine and a DNA vaccine have previously been tested experimentally against HSMI and demonstrated to give partial but not full protection. To understand the mechanisms involved in protection against HSMI ...